ESPE Abstracts

Central precocious puberty (CPP) caused by early maturation of the hypothalamic–pituitary–gonadal axis, resulting in early appearance of secondary sexual characteristics That affects children’s normal life and their adulthood’s final height. GnRH agonist therapy inhibits stimulating effects of endogenous GnRH by desensitizing hypophyseal gonadotropic cells and thus acceleration in bone maturation and early puberty is suppressed. So the aim of this longi...

Background: Poor sleep quality has been linked to insulin resistance and impaired glucose metabolism, but little is known about sleep and type 1 diabetes (T1D). People with T1D experience higher rates of sleep disturbances than people without diabetes, and these disturbances have negative implications on glycemic control, as well as psychosocial and cognitive outcomes.Objective: To study the prevalence of sleep disorders...

Background: type I diabetes is associated with progressive destruction of pancreatic β-cells with gradual decline of insulin secretion. C-peptide is considered the best indicator of endogenous insulin secretion in patients with diabetes.Aim of the Work: evaluate the effect of different variables associated with preserved pancreatic beta cell function at one year after diagnosis of children with type I DM.<p c...